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Western blotting and immunostaining of HTR subtypes will help us understand which ones are expressed on DP cells and therefore which can be applied to promote hair growth

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This phenomenon is further complicated by reported no observed adverse effect levels (NOAELs) that vary by 2–3 orders of magnitude across studies, likely reflecting differences in metabolic processing, genetic susceptibility, and methodological approaches ( 1.3 Objectives of this review This comprehensive review synthesizes current evidence (2019–2024) regarding EED-mediated reproductive toxicity in males, with particular emphasis on: Mechanistic Understanding: Elucidating the molecular pathways through which EEDs disrupt male reproductive function, including oxidative stress cascades, endocrine signaling interference, and epigenetic modifications