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however, the participation of laccase 2 (AGAP008731) and dopamine derivatives such as N -acetyl-dopamine (NADA) and N -β-alanyldopamine (NBAD) in mediating covalent crosslinks between cuticular proteins and/or between cuticular proteins and chitin fibers is exclusive to the sclerotization process 17,51
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In particular, NLRP3 is one of the most significant contributors to the development of nonalcoholic steatohepatitis (NASH) and liver fibrosis in mice [125]
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