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These are usually associated with high selectivity and affinity for the target, but also with high costs of production and purification, poor stabilization under SIP (sterilization-in-place) and CIP (cleaning-in-place) conditions, and potential leakage and end-product contamination (Clonis et al., 2000, Lowe, 2001, Roque and Lowe, 2006)
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The parallel presentation of mechanisms across tissue types highlights both unique specializations and common regulatory themes in adipose biology
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