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In terms of renal hypertrophic capacity, female mice exhibit larger kidney size and weight, as well as greater glomerular area, despite similar levels of renal IGF-1 and proliferating cell nuclear antigen (PCNA) expression.31 These sex differences in kidney size were attenuated in female mice lacking the estrogen receptor
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Renoprotection of dapagliflozin in human renal proximal tubular cells via the inhibition of the high mobility group box 1−Receptor for advanced glycation end products−Nuclear factor−Kb signaling pathway
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