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AKT activation leads to inhibition of nuclear factor kappa B (NF-κB), a transcription factor crucial in inflammation and fibrogеnеsis (48), This inhibition may be companied by a reducing in pro-inflammatory cytokines, such interleukin-6 (IL-6) and tumor necrosis factor- alpha (TNF-α) levels (49), While anti-inflammatory cytokines like interleukin-10 (IL-10) are increased

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We searched the human blood metabolome data against a library comprising predicted MS/MS spectra for all structures in the HMDB, or a combined library also including DeepMet structures

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