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Cntn4, a risk gene for neuropsychiatric disorders, modulates hippocampal synaptic plasticity and behavior
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In this context, dichloroacetate, a pyruvate dehydrogenase kinase (PDK) inhibitor, reverses the Warburg effect by a shift from glycolysis to mitochondrial oxidation, inducing a cytotoxic effect in various human malignant cell lines (164, 165)
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