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Damage to the RPE-Bruch membrane interface may lead to retinal antigen exposure, which triggers a localized inflammatory response [75,76] or may be associated with viral infections such as acute EBV or herpesvirus infections [77,78]

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Table of Contents Why the Evidence Gap Matters Now The Evidence Hierarchy: Four Tiers The Lasker Award and What It Means The Zagreb Problem The Harm Files The Enforcement Reckoning The Supply Chain Problem How to Evaluate Evidence Yourself The Genetics Factor Responsible Peptide Use in 2026 FAQs References Section 1: Why the Evidence Gap Matters Now The peptide industry hit an inflection point in late 2025 and the consequences are still unfolding