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Space flights are becoming longer, or as we have observed recently, there are unexpected delays in returning to Earth (astronauts Sunita Williams and Butch Wilmore spent 286 consecutive days in the space station), making such research increasingly necessary and relevant

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By utilizing different substrate combinations and inhibitors like Antimycin A, stigmatellin, myxothiazol, and a Rieske Fe-S knockout model, it was established that the Q o site of Complex III can also generate large amounts of O 2 • − (Brunelle et al., 2005)

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