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In individuals with depression, levels of antioxidants like vitamin E and coenzyme Q10 are often lower, which may diminish their ability to combat OS and indirectly affect RCT (135)
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8.6 Ferroptosis affects depression by regulating gut flora The brain-gut axis is a bidirectional communication network that connects cognitive and emotional functions of the brain to gut activity through neural pathways, neuroendocrine and neuroimmune systems, and gut microbiota (Mayer et al., 2022)
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