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As in other hemolytic anemias, patients with PKD can develop lowerextremity ulcers, usually medial in association with the medial malleolus, 29 which can be slow to heal or even fail to heal (Figure 2)
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A systematic review published in a 2025 orthopedic sports medicine journal, covering 35 preclinical studies, confirmed that BPC-157 reduced inflammatory cytokines and improved muscle injury outcomes
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