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Odds ratios for 10-unit increase in age, disease or insulin-treatment duration, and daily dose To investigate BR’s relationship with the LH-associated parameters in the absence of confounding factors, we separately analyzed subjects having BR only or LH only (Table 4), thus showing a significant association between BR and high HbA1c levels, missed injection site rotation, and long-standing insulin treatment

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The researchers showed that FOXO4-DRI treatment induced apoptosis specifically in senescent chondrocytes while sparing healthy proliferating cells, confirming the selectivity mechanism described in the original Baar et al