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186 Additionally, A-485, a CoA-competitive p300 inhibitor, decreases YY1 lactylation in human microglial clone 3 cells, ultimately hindering retinal neovascularization
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The results of this investigation demonstrate that pEXOs produced using the LEAP process can be safely administered to humans as an alternative therapy for wound healing, and they call for additional research in clinical trials created specifically to evaluate the therapeutic effectiveness in patients with retarded or interrupted wound healing (Johnson et al., 2023)
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