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The titre of the vector stocks was estimated to be 5.4 × 10 8 transducing units per ml for the Gsto2 -shRNA and 5.1 × 10 8 transducing units per ml for the scrambled shRNA
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Treg exhaustion or functional impairment, marked by altered expression of surface molecules such as CTLA-4, PD-1, and TIGIT, has been identified as a contributing factor to persistent ocular inflammation ( In therapeutic contexts, strategies focused on reestablishing regulatory T cell (Treg) homeostasis or enhancing their functionality have demonstrated potential in both preclinical and clinical environments
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