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However, both ‘resting state’ and ‘Hcy-gate’ structures are of inactive Cbl forms without any bound substrates, suggesting that they are more likely representative of the enzyme inactivated by oxidation and of the cob(I)alamin state before the binding of MeTHF

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TCE is characterized as carcinogenic to humans based on convincing evidence of a causal association between TCE exposure in humans and kidney cancer