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After mitochondrial damage, the mitochondrial matrix escapes into the cytoplasm, activates cGAS-STING, TLR9, and other signaling pathways, affects the differentiation and function of FLS, OBS, and OCS, destroys the homeostasis of bone metabolism, promotes the secretion of inflammatory factors, and promotes the development of RA (82)

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Oxalates, naturally occurring compounds found in many plant-based foods, have gained increasing attention in the functional medicine world due to their potential impact on health