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Taken together, these results support the idea that the levels of autophagy were further activated in the presence of glucose-free conditions and GPx1-shRNA, which indicates that the decreased GPx1 expression induced autophagic flux in PDA cells in response to glucose deprivation
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The tissue distribution results showed that the radioactivity intensity in most tissues peaked 1 h after administration, which was slightly later than the peak time of the total radioactivity concentration in plasma (0.167 h)
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