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In rat cerebral vessel, BMP9/ALK1 signaling increases expression of endothelial transporters such as organic anion transporting polypeptide 1a4 at the BBB ( Non-endothelial TGF-β Signaling in Cerebral Angiogenesis Cerebral angiogenesis is not only programmed in ECs, but also orchestrated by dynamic TGF-β signaling in other cell types within or outside the NVU, including pericytes, astrocytes, oligodendrocyte precursor cells, neural progenitors, preosteoblasts and periosteal dura cells
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