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If there is not enough calcium present in the bloodstream, the body will leach calcium from bones, weakening them
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Acting through the PAF receptor (PAFR) expressed on tumor cells, endothelial cells, and immune populations PAF induces inflammatory signaling, promotes vascular permeability, and facilitates tumor survival and metastasis, particularly under conditions of chemo or radiotherapy-induced stress (Chammas et al., 2017
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