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Thus, an intriguing dietary supplementation method would be to use NAC, VitD3, and Glut as alternative therapeutic agents to Lipoic Acid, as summarized in the diagram (Appendix A)

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The authors reported that co-treatment with N-acetylcysteine (NAC) partially rescued cell viability in both Mirk-depleted and control cells treated with cisplatin, underscoring the critical role of redox modulation in Mirk-targeted strategies

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